1118. Population Pharmacokinetics of Contezolid Acefosamil and Contezolid – Rationale for a Safe and Effective Loading Dose Regimen

BACKGROUND: Contezolid (CZD) is a novel oral oxazolidnone with comparable activity and potentially improved safety compared to current oxazolidinones. The intravenous (IV) double prodrug contezolid acefosamil (CZDa) is converted via MRX-1352 to active CZD. CZDa paired with CZD holds promise as a saf...

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Detalles Bibliográficos
Autores principales: Bulitta, Jürgen B, Hafkin, Barry, Fang, Edward
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2021
Materias:
Poster Abstracts
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8644342/
http://dx.doi.org/10.1093/ofid/ofab466.1311

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8644342/
http://dx.doi.org/10.1093/ofid/ofab466.1311

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