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998. Forward and Reverse Translational Approaches to Predict Efficacy of the Neutralizing Respiratory Syncytial Virus (RSV) Antibody MK-1654

BACKGROUND: MK-1654 is a respiratory syncytial virus (RSV) F glycoprotein neutralizing monoclonal antibody (mAb) with an extended half-life in late development to prevent RSV infection in infants. Neutralizing mAbs, like MK-1654, have great potential for prophylaxis against viral infection. However,...

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Detalles Bibliográficos
Autores principales: Maas, Brian M, Lommerse, Jos, Plock, Nele, Railkar, Radha, Amy Cheung, S Y, Caro, Luzelena, Chen, Jingxian, Liu, Wen, Zhang, Ying, Huang, Qinlei, Gao, Wei, Qin, Li, Meng, Jie, Witjes, Han, Schindler, Emilie, Guiastrennec, Benjamin, Bellanti, Francesco, Spellman, Daniel, Roadcap, Brad, Kalinova, Mariya, Fok-Seang, Juin, Catchpole, Andrew P, Espeseth, Amy, Aubrey Stoch, S, Lai, Eseng, Vora, Kalpit A, Aliprantis, Antonios O, Sachs, Jeffrey R
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8644347/
http://dx.doi.org/10.1093/ofid/ofab466.1192