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78. Non-Invasive Prediction of Invasive Fungal Infection by Plasma-Based Microbial Cell-Free DNA Next-Generation Sequencing (mcfDNA NGS) in Pediatric Patients with Relapsed or Refractory Leukemia

BACKGROUND: Diagnosis of invasive fungal infections (IFIs), a life-threatening complication of cancer therapy or hematopoietic cell transplantation (HCT) can be challenging, and IFI has poor outcomes. Prediction or early non-invasive diagnosis of IFI in high-risk hosts before onset of symptoms could...

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Detalles Bibliográficos
Autores principales: Wolf, Joshua, Maron, Gabriela, Goggin, Kathryn, Allison, Kim J, Merritt, Pamela, griffen, Amanda, Rubnitz, Jeffrey, Duttagupta, Radha, Brenner, Abigail, Blair, Lily, Ahmed, Asim A, Morin, Cara
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8644392/
http://dx.doi.org/10.1093/ofid/ofab466.078