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18. An Easy-to-Implement Clinical-Trial Frailty Index Based on Accumulation of Deficits: Validation in Zoster Clinical Trials

BACKGROUND: The impact of frailty on the efficacy and safety of vaccines and therapeutic interventions is increasingly recognized, yet assessment of frailty in clinical trials is often considered logistically challenging. We developed the retrospective Clinical Trial Frailty Index (CT-FI), using bas...

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Detalles Bibliográficos
Autores principales: Andrew, Melissa K, Matthews, Sean, Kim, Joon Hyung, Riley, Megan, Curran, Desmond
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8644468/
http://dx.doi.org/10.1093/ofid/ofab466.220