1055. ARGONAUT-IV: Susceptibility of Carbapenem-resistant Klebsiellae to Ceftibuten/VNRX-5236

BACKGROUND: Carbapenem resistance in Klebsiellae spp. arises through mutational and acquired mechanisms and is considered an “urgent threat” by the CDC. VNRX-5236 is a bicyclic boronate β-lactamase inhibitor (BLI) that combines oral bioavailability (via etzadroxil prodrug VNRX-7145; Figure 1) and ac...

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Detalles Bibliográficos
Autores principales: Mack, Andrew R, Bethel, Christopher, Marshall, Steven, Patel, Robin, van Duin, David, Fowler, Vance G, Rhoads, Daniel D, Jacobs, Michael, van den Akker, Focco, Six, David A, Moeck, Greg, Papp-Wallace, Krisztina M, Bonomo, Robert A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2021
Materias:
Poster Abstracts
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8644492/
http://dx.doi.org/10.1093/ofid/ofab466.1249

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8644492/
http://dx.doi.org/10.1093/ofid/ofab466.1249

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