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523. Use of Immune-Viral Dynamics Modeling to Understand Molnupiravir Drug Effect for COVID-19

BACKGROUND: Molnupiravir (MOV) is an orally administered ribonucleoside prodrug of β-D-N4-hydroxycytidine (NHC) against SARS-CoV-2. Here we present viral dynamics analysis of Phase 2 clinical virology data to inform MOV Phase 3 study design and development strategy. METHODS: An Immune-Viral Dynamics...

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Detalles Bibliográficos
Autores principales: Cao, Youfang, Gao, Wei, Birger, Ruthie, Stone, Julie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8644542/
http://dx.doi.org/10.1093/ofid/ofab466.722