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523. Use of Immune-Viral Dynamics Modeling to Understand Molnupiravir Drug Effect for COVID-19
BACKGROUND: Molnupiravir (MOV) is an orally administered ribonucleoside prodrug of β-D-N4-hydroxycytidine (NHC) against SARS-CoV-2. Here we present viral dynamics analysis of Phase 2 clinical virology data to inform MOV Phase 3 study design and development strategy. METHODS: An Immune-Viral Dynamics...
Autores principales: | Cao, Youfang, Gao, Wei, Birger, Ruthie, Stone, Julie |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8644542/ http://dx.doi.org/10.1093/ofid/ofab466.722 |
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