1087. Imipenem-Cilastatin-Relebactam (I/R) Pharmacokinetics (PK) in Critically Ill Patients with Augmented Renal Clearance (ARC)

BACKGROUND: Imipenem (IMI) and relebactam (REL) are predominantly excreted via glomerular filtration. ARC is a common syndrome in critically ill patients with sepsis, whereby increased renal blood flow may result in enhanced solute clearance; therefore, sub-therapeutic antibiotic concentrations are...

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Detalles Bibliográficos
Autores principales: Fratoni, Andrew J, Mah, John W, Nicolau, David P, Kuti, Joseph L
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2021
Materias:
Poster Abstracts
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8644632/
http://dx.doi.org/10.1093/ofid/ofab466.1281

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8644632/
http://dx.doi.org/10.1093/ofid/ofab466.1281

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