1122. Effect of Aluminum Hydroxide/Magnesium Hydroxide/Simethicone and Omeprazole on the Pharmacokinetics of Tebipenem Pivoxil Hydrobromide (TBP-PI-HBr) in Healthy Adult Subjects

BACKGROUND: Tebipenem pivoxil hydrobromide (TBP-PI-HBr) is an oral prodrug that is converted to tebipenem (TBP), the active moiety being developed for treating complication urinary tract infections. Antacids and proton pump inhibitors are known to change gastric pH after administration, which could...

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Detalles Bibliográficos
Autores principales: Gupta, Vipul K, Patel, Gina, Gasink, Leanne, Bajraktari, Floni, Lei, Yang, Jain, Akash, Srivastava, Praveen, Talley, Angela
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2021
Materias:
Poster Abstracts
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8644648/
http://dx.doi.org/10.1093/ofid/ofab466.1315

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8644648/
http://dx.doi.org/10.1093/ofid/ofab466.1315

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