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1183. Serum Bactericidal Activity Induced by Live Attenuated Pertussis Vaccine BPZE1 is Comparable to Boostrix™

BACKGROUND: In a Phase 2b, multi-center, placebo-controlled, randomized study, intranasal BPZE1 induced mucosal and serum antibodies to pertussis antigens and protected against subsequent colonization following attenuated challenge with BPZE1 3 months later. Boostrix(TM) also induced serum but not m...

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Detalles Bibliográficos
Autores principales: Keech, Cheryl A, Gorringe, Andrew, Cavell, Breeze, Goldstein, Peter, Rubin, Keith
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8644680/
http://dx.doi.org/10.1093/ofid/ofab466.1375