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1183. Serum Bactericidal Activity Induced by Live Attenuated Pertussis Vaccine BPZE1 is Comparable to Boostrix™
BACKGROUND: In a Phase 2b, multi-center, placebo-controlled, randomized study, intranasal BPZE1 induced mucosal and serum antibodies to pertussis antigens and protected against subsequent colonization following attenuated challenge with BPZE1 3 months later. Boostrix(TM) also induced serum but not m...
Autores principales: | Keech, Cheryl A, Gorringe, Andrew, Cavell, Breeze, Goldstein, Peter, Rubin, Keith |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8644680/ http://dx.doi.org/10.1093/ofid/ofab466.1375 |
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