579. Design and Immunogenicity of a Pan-SARS-CoV-2 Synthetic DNA Vaccine

BACKGROUND: First-generation COVID-19 vaccines are matched to spike protein of the Wuhan-H1 (WT) strain. Convalescent and vaccinee samples show reduced neutralization of SARS-CoV-2 variants of concern (VOC). Next generation DNA vaccines could be matched to single variants or synthetically designed f...

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Detalles Bibliográficos
Autores principales: Schultheis, Katherine, Reed, Charles C, Andrade, Viviane M, Kalia, Richa, Tur, Jared, Schouest, Blake, Elwood, Dustin, Maricic, Igor, Doan, Arthur, Eblimit, Zeena, Pezzoli, Patrick, Amante, Dinah, yang, maria, Fader, Joseph g, Ferrer, Roi, Weiner, David, Kim, J Joseph, Humeau, Laurent, Ramos, Stephanie, Smith, Trevor R F, Broderick, Kate
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2021
Materias:
Poster Abstracts
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8644724/
http://dx.doi.org/10.1093/ofid/ofab466.777

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8644724/
http://dx.doi.org/10.1093/ofid/ofab466.777

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