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579. Design and Immunogenicity of a Pan-SARS-CoV-2 Synthetic DNA Vaccine
BACKGROUND: First-generation COVID-19 vaccines are matched to spike protein of the Wuhan-H1 (WT) strain. Convalescent and vaccinee samples show reduced neutralization of SARS-CoV-2 variants of concern (VOC). Next generation DNA vaccines could be matched to single variants or synthetically designed f...
Autores principales: | Schultheis, Katherine, Reed, Charles C, Andrade, Viviane M, Kalia, Richa, Tur, Jared, Schouest, Blake, Elwood, Dustin, Maricic, Igor, Doan, Arthur, Eblimit, Zeena, Pezzoli, Patrick, Amante, Dinah, yang, maria, Fader, Joseph g, Ferrer, Roi, Weiner, David, Kim, J Joseph, Humeau, Laurent, Ramos, Stephanie, Smith, Trevor R F, Broderick, Kate |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8644724/ http://dx.doi.org/10.1093/ofid/ofab466.777 |
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