178. Endemic Carbapenem Resistance Driven By Clonal and Horizontal Spread of bla(IMP-4) Across Diverse Enterobacterales: Jumping Genes, Promiscuous Plasmids and Killer Clones

BACKGROUND: Carbapenem-resistant Enterobacterales (CRE) have become endemic and cause significant morbidity and mortality globally. The metallo-beta-lactamase gene bla(IMP-4) is a key CRE resistance determinant in Australia and Asia but its genomic context remains unknown. We aimed to determine the...

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Detalles Bibliográficos
Autores principales: Macesic, Nenad, Blakeway, Luke, Jenney, Adam W, Peleg, Anton
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2021
Materias:
Oral Abstracts
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8644749/
http://dx.doi.org/10.1093/ofid/ofab466.178

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8644749/
http://dx.doi.org/10.1093/ofid/ofab466.178

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