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178. Endemic Carbapenem Resistance Driven By Clonal and Horizontal Spread of bla(IMP-4) Across Diverse Enterobacterales: Jumping Genes, Promiscuous Plasmids and Killer Clones
BACKGROUND: Carbapenem-resistant Enterobacterales (CRE) have become endemic and cause significant morbidity and mortality globally. The metallo-beta-lactamase gene bla(IMP-4) is a key CRE resistance determinant in Australia and Asia but its genomic context remains unknown. We aimed to determine the...
Autores principales: | Macesic, Nenad, Blakeway, Luke, Jenney, Adam W, Peleg, Anton |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8644749/ http://dx.doi.org/10.1093/ofid/ofab466.178 |
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