Cargando…

584. Phase 1 Placebo-Controlled Trial of COVI-VAC™, an Intranasal, Live Attenuated COVID-19 Vaccine

BACKGROUND: COVI-VAC(TM) is an intra-nasal live-attenuated SARS-COV-2 synthetic viral vaccine being developed for the prevention of COVID-19. COVI-VAC is attenuated through deletion of the furin cleavage site and introduction of 283 silent deoptimizing mutations that maintain viral amino acid sequen...

Descripción completa

Detalles Bibliográficos
Autores principales:	Tasker, Sybil, Bendel, Daryl, Bevan, Melissa, Mueller, Steffen, Kushnir, Anna, Londt, Brandon, Robert Coleman, J
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2021
Materias:	Poster Abstracts
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8644858/ http://dx.doi.org/10.1093/ofid/ofab466.782

Ejemplares similares

577. COVI-VAC™, a Live Attenuated COVID-19 Vaccine, Provides Single Dose Protection Against Heterologous Challenge with SARS-CoV-2 Beta (B.1.351) in the Syrian Golden Hamster Model
por: Kushnir, Anna, et al.
Publicado: (2021)

1938. CoviLiv™, a Novel Intranasal Live-Attenuated COVID-19 Vaccine Candidate, Induces Robust Humoral and Cellular Immunity in First-In-Human Clinical Trial CDX-CoV-001
por: Kaufmann, Johanna K, et al.
Publicado: (2023)

Scalable live-attenuated SARS-CoV-2 vaccine candidate demonstrates preclinical safety and efficacy
por: Wang, Ying, et al.
Publicado: (2021)

Gam-COVID-Vac, EpiVacCorona, and CoviVac effectiveness against lung injury during Delta and Omicron variant surges in St. Petersburg, Russia: a test-negative case–control study
por: Barchuk, Anton, et al.
Publicado: (2022)

Long-term humoral immunogenicity, safety and protective efficacy of inactivated vaccine against COVID-19 (CoviVac) in preclinical studies
por: Kozlovskaya, Liubov I., et al.
Publicado: (2021)

Safety and Immunogenicity of Inactivated Whole Virion COVID-19 Vaccine CoviVac in Clinical Trials in 18–60 and 60+ Age Cohorts
por: Gordeychuk, Ilya V., et al.
Publicado: (2023)

Position statement on COViD-19 infection and Diabetes
Publicado: (2020)

Live-attenuated H1N1 influenza vaccine candidate displays potent efficacy in mice and ferrets
por: Stauft, Charles B., et al.
Publicado: (2019)

SUN-584 Unusual Presentation Of Myxedema Coma
por: Murati, Jonila, et al.
Publicado: (2019)

SUN-584 Micrornas in Brown and White Adipocytes
por: Dimitri, Federica, et al.
Publicado: (2020)

2554. Safety and Immunogenicity of NasoVAX, a Novel Intranasal Influenza Vaccine
por: Tasker, Sybil, et al.
Publicado: (2018)

A few thoughts and evidence on the COViD-19 pandemic
por: Stahl, J.P.
Publicado: (2020)

MON-584 Albuminuria and Obesity - Which Are the Associated Factors?
por: Costa, Cláudia Fernandes, et al.
Publicado: (2020)

584. Ventricular assist device infections with Pseudomonas aeruginosa
por: Roberts, Scott C, et al.
Publicado: (2020)

Compliance of a cobalt chromium coronary stent alloy – the COVIS trial
por: Hagemeister, Jens, et al.
Publicado: (2005)

584. Investigation of the Association Between Neurocognitive Function and Depression in HIV Infection
por: Mumford, Brigid, et al.
Publicado: (2018)

MON-584 Iodine Nutrition Status in Pregnancy: Is the Situation in Poland Improving?
por: Trofimiuk-Muldner, Malgorzata, et al.
Publicado: (2019)

Collaborative Overview of coronaVIrus impact on ORTHopaedic training in the UK (COVI - ORTH UK)
por: Jayatilaka, Malwattage Lara Tania, et al.
Publicado: (2021)

CoviExpert: COVID-19 detection from chest X-ray using CNN
por: Arivoli, A., et al.
Publicado: (2022)

Safety and Immunogenicity of a Novel Intranasal Influenza Vaccine (NasoVAX): A Phase 2 Randomized, Controlled Trial
por: Tasker, Sybil, et al.
Publicado: (2021)

REPORT ON IS584 Beta-decay study of neutron-rich Tl and Pb isotopes
por: Gottardo, Andrea, et al.
Publicado: (2019)

PT584. Peripheral inflammatory markers in Alzheimer’s disease and mild cognitive impairment
por: Kim, Yo Sup, et al.
Publicado: (2016)

Fluctuating expression of miR-584 in primary and high-grade gastric cancer
por: Ebrahimi Ghahnavieh, Laleh, et al.
Publicado: (2020)

Complete Genome Sequence of Bartonella bacilliformis Strain KC584 (ATCC 35686)
por: Dichter, Alexander A., et al.
Publicado: (2020)

The impact of race and ethnicity on outcomes in 19,584 adults hospitalized with COVID-19
por: Navar, Ann M., et al.
Publicado: (2021)

584 Where Are They Now? - A Single-Center Survey of Burn Surgery Fellow Graduates
por: Prophete, Justine, et al.
Publicado: (2022)

Respiratory PCR detects influenza after intranasal live-attenuated influenza vaccination
por: Lumley, S, et al.
Publicado: (2013)

COVI-Prim survey: Challenges for Austrian and German general practitioners during initial phase of COVID-19
por: Siebenhofer, Andrea, et al.
Publicado: (2021)

A comprehensive study of Ecuadorian adult patients with a mild and moderate presentation of COViD-19
por: González-Andrade, Fabricio, et al.
Publicado: (2023)

Treatment with Helicobacter pylori-derived VacA attenuates allergic airway disease
por: Reuter, Sebastian, et al.
Publicado: (2023)

Le vaccin chinois CoronaVac® à l’épreuve contre placebo en Turquie
por: Manus, Jean-Marie
Publicado: (2021)

SAT-584 Uc.336-As Inhibits White Adipocyte Differentiation and Promotes White to Brown Conversion
por: Li, Yanbing, et al.
Publicado: (2020)

Critical comments on COViD-19 outbreak: succinct advice for dentists and oral healthcare professionals by Cirillo (2020)
por: Kasar, Vandan R, et al.
Publicado: (2020)

COVI-Prim Longitudinal Survey: Experiences of Primary Care Physicians During the Early Phase of the COVID-19 Pandemic
por: Schaffler-Schaden, Dagmar, et al.
Publicado: (2022)

Pulmonary Embolism in Post-CoviD-19 Patients, a Literature Review: Red Flag for Increased Awareness?
por: Mouzarou, Angeliki, et al.
Publicado: (2022)

Experiences from COVID-19-driven use of telephone consultations in a cardiology clinic—The CoviTel study
por: Hundebøll, Astrid Brink, et al.
Publicado: (2022)

Post Traumatic Growth as a way of mastering COViD-19 Peritraumatic Distress Inde[ (in Russian sample)
por: Kvasova, O., et al.
Publicado: (2022)

Use of intranasal live attenuated influenza vaccine in individuals with asthma or a history of wheezing
por: Ambrose, Christopher S.
Publicado: (2012)

Acceptability of intranasal live attenuated influenza vaccine, influenza knowledge and vaccine intent in The Gambia
por: Armitage, Edwin P., et al.
Publicado: (2018)

Cost-Effectiveness of Intranasal Live-Attenuated Influenza Vaccine for Children: A Systematic Review
por: Chan, Kenneth Sik-Kwan, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_11b844idn37vb385tt2qos9n39