1053. The β-Lactamase Inhibitor QPX7728 Restores the Activity of β-Lactam Agents against Contemporary Extended-Spectrum β-lactamase (ESBL)-Producing and Carbapenem-Resistant Enterobacterales (CRE) Isolates, Including Isolates Producing Metallo-β-lactamases

BACKGROUND: The β-lactam (BL)/ β-lactamase inhibitor (BLI) combinations approved in the last 10 years are active against most ESBL-producing Enterobacterales (ENT) and CRE isolates, but have limited activity against metallo-β-lactamase (MBL)-producing ENT. We evaluated the activity of QPX7728 (QPX),...

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Detalles Bibliográficos
Autores principales: Lindley, Jill, Edah, Yahse, Lomovskaya, Olga, Castanheira, Mariana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2021
Materias:
Poster Abstracts
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8644884/
http://dx.doi.org/10.1093/ofid/ofab466.1247

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8644884/
http://dx.doi.org/10.1093/ofid/ofab466.1247

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