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1100. A Prospective Evaluation of Neurotoxicity Among Patients Receiving Dose-Optimized Cefepime or Meropenem With Concomitant Therapeutic Drug Monitoring

BACKGROUND: Cefepime (FEP) induced neurotoxicity (NT) may have serious implications for patients (pts). Retrospective studies have employed variable definitions of NT, finding renal impairment and FEP trough concentrations (Cmin) > 20 mg/L as risk factors. Prospective studies comparing antibiotic...

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Detalles Bibliográficos
Autores principales: Smith, Brandon, Kline, Ellen G, Shutter, Lori, Fong-Isariyawongse, Joanna, Urban, Alexandra, Murray, Holt, Byers, Karin, Shields, Ryan K
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2021
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Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8644903/
http://dx.doi.org/10.1093/ofid/ofab466.1294