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Ultrasound triggered topical delivery of Bmp7 mRNA for white fat browning induction via engineered smart exosomes

BACKGROUND: Efficient and topical delivery of drugs is essential for maximized efficacy and minimized toxicity. In this study, we aimed to design an exosome-based drug delivery platform endowed with the ability of escaping from phagocytosis at non-target organs and controllably releasing drugs at ta...

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Detalles Bibliográficos
Autores principales: Guo, Yitong, Wan, Zhuo, Zhao, Ping, Wei, Mengying, Liu, Yunnan, Bu, Te, Sun, Wenqi, Li, Zhelong, Yuan, Lijun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8645082/
https://www.ncbi.nlm.nih.gov/pubmed/34863187
http://dx.doi.org/10.1186/s12951-021-01145-3