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Ethionine-mediated reduction of S-adenosylmethionine is responsible for the neural tube defects in the developing mouse embryo-mediated m6A modification and is involved in neural tube defects via modulating Wnt/β-catenin signaling pathway

Neural tube defects (NTDs) remain one of the most life-threatening birth defects affecting infants. Most patients with NTDs eventually develop lifelong disability, which cause significant morbidity and mortality and seriously reduce the quality of life. Our previous study has found that ethionine in...

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Detalles Bibliográficos
Autores principales: Zhang, Li, Cao, Rui, Li, Dandan, Sun, Yuqing, Zhang, Juan, Wang, Xiuwei, Khan, Ajab, Liu, Zhizhen, Niu, Bo, Xu, Jun, Xie, Jun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8645112/
https://www.ncbi.nlm.nih.gov/pubmed/34863249
http://dx.doi.org/10.1186/s13072-021-00426-3