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The high methylation level of a novel 151-bp CpG island in the ESR1 gene promoter is associated with a poor breast cancer prognosis

BACKGROUND: The ESR1 gene suffers methylation changes in many types of cancers, including breast cancer (BC), the most frequently diagnosed cancer in women that is also present in men. Methylation at promoter A of ESR1 is the worse prognosis in terms of overall survival; thus, the early detection, p...

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Detalles Bibliográficos
Autores principales: Quintas-Granados, Laura Itzel, Cortés, Hernán, Carmen, Manuel González-Del, Leyva-Gómez, Gerardo, Bustamante-Montes, Lilia Patricia, Rodríguez-Morales, Miguel, Villegas-Vazquez, Edgar Yebran, López-Reyes, Israel, Alcaraz-Estrada, Sofía Lizeth, Sandoval-Basilio, Jorge, Soto-Reyes, Ernesto, Sharifi-Rad, Javad, Figueroa-González, Gabriela, Reyes-Hernández, Octavio Daniel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8645138/
https://www.ncbi.nlm.nih.gov/pubmed/34863151
http://dx.doi.org/10.1186/s12935-021-02343-7