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Epigenetic alterations associated with dexamethasone sodium phosphate through DNMT and TET in RPE cells

PURPOSE: To elucidate the mechanism behind epigenetic alteration associated with dexamethasone (DEX) sodium phosphate treatment. METHODS: We performed enzyme-linked immunosorbent assay to quantify changes in global DNA methylation and hydroxymethylation, quantitative real-time PCR (qRT-PCR) of the D...

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Detalles Bibliográficos
Autores principales: Liu, Wenjie, Mohan, Sruthi Priya, Nagaraj, Nareshkumar Ragavachetty, Sundar Jaganathan, Shyam, Wen, Yi, Ramasubramanyan, Sharada, Irudayaraj, Joseph
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Molecular Vision 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8645185/
https://www.ncbi.nlm.nih.gov/pubmed/34924744