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Development of a simple and miniaturized sandwich-like fluorescence polarization assay for rapid screening of SARS-CoV-2 main protease inhibitors

BACKGROUND: Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is highly transmissible and has caused a pandemic named coronavirus disease 2019 (COVID-19), which has quickly spread worldwide. Although several therapeutic agents have been evaluated or approved for the treatment of COVID-19...

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Detalles Bibliográficos
Autores principales: Yan, Gangan, Li, Dongsheng, Lin, Yuan, Fu, Zhenghao, Qi, Haiyan, Liu, Xiaoping, Zhang, Jing, Si, Shuyi, Chen, Yunyu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8645223/
https://www.ncbi.nlm.nih.gov/pubmed/34865653
http://dx.doi.org/10.1186/s13578-021-00720-3