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A cytosolic reductase pathway is required for efficient N-glycosylation of an STT3B-dependent acceptor site

N-linked glycosylation of proteins entering the secretory pathway is an essential modification required for protein stability and function. Previously, it has been shown that there is a temporal relationship between protein folding and glycosylation, which influences the occupancy of specific glycos...

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Detalles Bibliográficos
Autores principales: van Lith, Marcel, Pringle, Marie Anne, Fleming, Bethany, Gaeta, Giorgia, Im, Jisu, Gilmore, Reid, Bulleid, Neil J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists Ltd 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8645230/
https://www.ncbi.nlm.nih.gov/pubmed/34734627
http://dx.doi.org/10.1242/jcs.259340