Cargando…

p38 regulates the tumor suppressor PDCD4 via the TSC-mTORC1 pathway

Programmed cell death protein 4 (PDCD4) exerts critical functions as tumor suppressor and in immune cells to regulate inflammatory processes. The phosphoinositide 3-kinase (PI3K) promotes degradation of PDCD4 via mammalian target of rapamycin complex 1 (mTORC1). However, additional pathways that may...

Descripción completa

Detalles Bibliográficos
Autores principales: Braun, Clarissa, Katholnig, Karl, Kaltenecker, Christopher, Linke, Monika, Sukhbaatar, Nyamdelger, Hengstschläger, Markus, Weichhart, Thomas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Shared Science Publishers OG 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8645265/
https://www.ncbi.nlm.nih.gov/pubmed/34917890
http://dx.doi.org/10.15698/cst2021.12.260