Expression of sterile-α and armadillo motif containing protein (SARM) in rheumatoid arthritis monocytes correlates with TLR2-induced IL-1β and disease activity

OBJECTIVE: Cartilage and bone damage in RA are associated with elevated IL-1β. The effects of IL-1β can be reduced by biological therapies that target IL-1β or TNF-α. However, the mechanisms responsible for increased IL-1β and the effect of anti-TNF-α have not been fully elucidated. Recently, steril...

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Detalles Bibliográficos
Autores principales: Thwaites, Ryan S, Unterberger, Sarah, Chamberlain, Giselle, Gray, Henry, Jordan, Kelsey, Davies, Kevin A, Harrison, Neil A, Sacre, Sandra
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2021
Materias:
Basic Science
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8645275/
https://www.ncbi.nlm.nih.gov/pubmed/33605409
http://dx.doi.org/10.1093/rheumatology/keab162

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8645275/
https://www.ncbi.nlm.nih.gov/pubmed/33605409
http://dx.doi.org/10.1093/rheumatology/keab162

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