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The role of the sphingosine axis in immune regulation: A dichotomy in the anti-inflammatory effects between sphingosine kinase 1 and sphingosine kinase 2-dependent pathways

Background: Sphingosine kinase has been identified as playing a central role in the immune cascade, being a common mediator in the cellular response to a variety of signals. The different effects of sphingosine kinase 1 and 2 (SphK1 and SphK2, respectively) activity have not been completely characte...

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Detalles Bibliográficos
Autores principales: Ishay, Yuval, Rotnemer-Golinkin, Dvorah, Ilan, Yaron
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8645305/
https://www.ncbi.nlm.nih.gov/pubmed/34789044
http://dx.doi.org/10.1177/20587384211053274