Benchmarking a highly selective USP30 inhibitor for enhancement of mitophagy and pexophagy

The deubiquitylase USP30 is an actionable target considered for treatment of conditions associated with defects in the PINK1-PRKN pathway leading to mitophagy. We provide a detailed cell biological characterization of a benzosulphonamide molecule, compound 39, that has previously been reported to in...

Descripción completa

Detalles Bibliográficos
Autores principales: Rusilowicz-Jones, Emma V, Barone, Francesco G, Lopes, Fernanda Martins, Stephen, Elezabeth, Mortiboys, Heather, Urbé, Sylvie, Clague, Michael J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Life Science Alliance LLC 2021
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8645336/
https://www.ncbi.nlm.nih.gov/pubmed/34844982
http://dx.doi.org/10.26508/lsa.202101287

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8645336/
https://www.ncbi.nlm.nih.gov/pubmed/34844982
http://dx.doi.org/10.26508/lsa.202101287

Ejemplares similares