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30 year experience of index case identification and outcomes of cascade testing in high-risk breast and colorectal cancer predisposition genes

It is 30 years since the first diagnostic cancer predisposition gene (CPG) test in the Manchester Centre for Genomic Medicine (MCGM), providing opportunities for cancer prevention, early detection and targeted treatments in index cases and at-risk family members. Here, we present time trends (1990–2...

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Detalles Bibliográficos
Autores principales: Woodward, Emma R., Green, Kate, Burghel, George J., Bulman, Michael, Clancy, Tara, Lalloo, Fiona, Schlecht, Helene, Wallace, Andrew J., Evans, D. Gareth
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8645350/
https://www.ncbi.nlm.nih.gov/pubmed/34866136
http://dx.doi.org/10.1038/s41431-021-01011-8