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Molecular characterization of type I IFN-induced cytotoxicity in bladder cancer cells reveals biomarkers of resistance

Although anti-tumor activities of type I interferons (IFNs) have been recognized for decades, the molecular mechanisms contributing to clinical response remain poorly understood. The complex functions of these pleiotropic cytokines include stimulation of innate and adaptive immune responses against...

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Detalles Bibliográficos
Autores principales: Green, Jennifer L., Osterhout, Robin E., Klova, Amy L., Merkwirth, Carsten, McDonnell, Scott R.P., Zavareh, Reza Beheshti, Fuchs, Bryan C., Kamal, Adeela, Jakobsen, Jørn S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Gene & Cell Therapy 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8645427/
https://www.ncbi.nlm.nih.gov/pubmed/34938855
http://dx.doi.org/10.1016/j.omto.2021.11.006