Inhibition of GTPase Rac1 expression by vitamin D mitigates pressure overload-induced cardiac hypertrophy

BACKGROUND: 1, 25-dihydroxy Vitamin D3 (VitD) attenuates left ventricular hypertrophy (LVH), but the mechanisms remain to be portrayed in-depth. The small GTPase Rac1 plays a pivotal role in cardiovascular pathology, especially LVH. Here, we tested whether VitD exerts its anti-LVH effects by counter...

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Detalles Bibliográficos
Autores principales: Moradi, Ali, Maroofi, Abdulbaset, Hemati, Mahdie, Hashemzade, Tahmine, Alborzi, Nasrin, Safari, Fatemeh
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Original Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8645456/
https://www.ncbi.nlm.nih.gov/pubmed/34917751
http://dx.doi.org/10.1016/j.ijcha.2021.100922

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8645456/
https://www.ncbi.nlm.nih.gov/pubmed/34917751
http://dx.doi.org/10.1016/j.ijcha.2021.100922

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