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Synergistic and additive interactions between receptor signaling networks drive the regulatory T cell versus T helper 17 cell fate choice
CD4+ T cells differentiate into subsets that promote immunity or minimize damage to the host. T helper 17 cells (Th17) are effector cells that function in inflammatory responses. T regulatory cells (Tregs) maintain tolerance and prevent autoimmunity by secreting immunosuppressive cytokines and expre...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society for Biochemistry and Molecular Biology
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8645459/ https://www.ncbi.nlm.nih.gov/pubmed/34688667 http://dx.doi.org/10.1016/j.jbc.2021.101330 |