Synergistic and additive interactions between receptor signaling networks drive the regulatory T cell versus T helper 17 cell fate choice

CD4+ T cells differentiate into subsets that promote immunity or minimize damage to the host. T helper 17 cells (Th17) are effector cells that function in inflammatory responses. T regulatory cells (Tregs) maintain tolerance and prevent autoimmunity by secreting immunosuppressive cytokines and expre...

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Detalles Bibliográficos
Autores principales: Prado, Douglas S., Cattley, Richard T., Shipman, Corey W., Happe, Cassandra, Lee, Mijoon, Boggess, William C., MacDonald, Matthew L., Hawse, William F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8645459/
https://www.ncbi.nlm.nih.gov/pubmed/34688667
http://dx.doi.org/10.1016/j.jbc.2021.101330

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