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Estrogen Receptor 1 Inhibition of Wnt/β-Catenin Signaling Contributes to Sex Differences in Hepatocarcinogenesis

BACKGROUND: Hepatocellular Carcinoma (HCC) is a sexually dimorphic cancer, with female sex being independently protective against HCC incidence and progression. The aim of our study was to understand the mechanism of estrogen receptor signaling in driving sex differences in hepatocarcinogenesis. MET...

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Detalles Bibliográficos
Autores principales: Bhat, Mamatha, Pasini, Elisa, Pastrello, Chiara, Angeli, Marc, Baciu, Cristina, Abovsky, Mark, Coffee, Angella, Adeyi, Oyedele, Kotlyar, Max, Jurisica, Igor
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8645636/
https://www.ncbi.nlm.nih.gov/pubmed/34881186
http://dx.doi.org/10.3389/fonc.2021.777834