Metformin Downregulates PD-L1 Expression in Esophageal Squamous Cell Carcinoma by Inhibiting IL-6 Signaling Pathway

PURPOSE: To characterize the mechanism by which metformin inhibits PD-L1 expression in esophageal squamous cell carcinoma (ESCC) and to evaluate the effect of metformin on the antitumor immune response. METHODS: The Cancer Genome Atlas (TCGA) database was used to analyze the correlations between IL-...

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Detalles Bibliográficos
Autores principales: Lu, Yao, Xin, Dao, Guan, Lulu, Xu, Mengli, Yang, Yalan, Chen, Yu, Yang, Yuanyuan, Wang-Gillam, Andrea, Wang, Li, Zong, Shanggang, Wang, Feng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Oncology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8645640/
https://www.ncbi.nlm.nih.gov/pubmed/34881181
http://dx.doi.org/10.3389/fonc.2021.762523

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8645640/
https://www.ncbi.nlm.nih.gov/pubmed/34881181
http://dx.doi.org/10.3389/fonc.2021.762523

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