C/EBPβ induces B‐cell acute lymphoblastic leukemia and cooperates with BLNK mutations

BLNK (BASH/SLP‐65) encodes an adaptor protein that plays an important role in B‐cell receptor (BCR) signaling. Loss‐of‐function mutations in this gene are observed in human pre‐B acute lymphoblastic leukemia (ALL), and a subset of Blnk knock‐out (KO) mice develop pre‐B‐ALL. To understand the molecul...

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Detalles Bibliográficos
Autores principales: Kurata, Morito, Onishi, Iichiro, Takahara, Tomoko, Yamazaki, Yukari, Ishibashi, Sachiko, Goitsuka, Ryo, Kitamura, Daisuke, Takita, Junko, Hayashi, Yasuhide, Largaesapda, David A, Kitagawa, Masanobu, Nakamura, Takuro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8645713/
https://www.ncbi.nlm.nih.gov/pubmed/34653294
http://dx.doi.org/10.1111/cas.15164

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8645713/
https://www.ncbi.nlm.nih.gov/pubmed/34653294
http://dx.doi.org/10.1111/cas.15164

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