Cargando…

C/EBPβ induces B‐cell acute lymphoblastic leukemia and cooperates with BLNK mutations

BLNK (BASH/SLP‐65) encodes an adaptor protein that plays an important role in B‐cell receptor (BCR) signaling. Loss‐of‐function mutations in this gene are observed in human pre‐B acute lymphoblastic leukemia (ALL), and a subset of Blnk knock‐out (KO) mice develop pre‐B‐ALL. To understand the molecul...

Descripción completa

Detalles Bibliográficos
Autores principales:	Kurata, Morito, Onishi, Iichiro, Takahara, Tomoko, Yamazaki, Yukari, Ishibashi, Sachiko, Goitsuka, Ryo, Kitamura, Daisuke, Takita, Junko, Hayashi, Yasuhide, Largaesapda, David A, Kitagawa, Masanobu, Nakamura, Takuro
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley and Sons Inc. 2021
Materias:	Original Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8645713/ https://www.ncbi.nlm.nih.gov/pubmed/34653294 http://dx.doi.org/10.1111/cas.15164

Ejemplares similares

CRISPR screening identifies M1AP as a new MYC regulator with a promoter-reporter system
por: Yamamoto, Akiko, et al.
Publicado: (2020)

Bone marrow niches in myeloid neoplasms
por: Kitagawa, Masanobu, et al.
Publicado: (2019)

Identification of CMTM7 as a Transmembrane Linker of BLNK and the B-Cell Receptor
por: Miyazaki, Atsuko, et al.
Publicado: (2012)

To Discover the Efficient and Novel Drug Targets in Human Cancers Using CRISPR/Cas Screening and Databases
por: Onishi, Iichiroh, et al.
Publicado: (2021)

Efficient Identification of the MYC Regulator with the Use of the CRISPR Library and Context-Matched Database Screenings
por: Tanaka, Yosuke, et al.
Publicado: (2022)

Identification and characterisation of the immune response properties of Lampetra japonica BLNK
por: Han, Yinglun, et al.
Publicado: (2016)

Regulation of 4-HNE via SMARCA4 Is Associated with Worse Clinical Outcomes in Hepatocellular Carcinoma
por: Watabe, Shiori, et al.
Publicado: (2023)

Prognostic significance of leukopenia in childhood acute lymphoblastic leukemia
por: SHIOZAWA, YUSUKE, et al.
Publicado: (2014)

Identification of NRAS Downstream Genes with CRISPR Activation Screening
por: Tatsumi, Akiya, et al.
Publicado: (2022)

Anti-apoptotic function of Xbp1 as an IL-3 signaling molecule in hematopoietic cells
por: Kurata, M, et al.
Publicado: (2011)

BLNK mutation associated with T-cell LGL leukemia and autoimmune diseases: Case report in hematology
por: Fouquet, Guillemette, et al.
Publicado: (2022)

Indirect CRISPR screening with photoconversion revealed key factors of drug resistance with cell–cell interactions
por: Sugita, Keisuke, et al.
Publicado: (2023)

BLNK/BTK: Novel Components in the NF-kappa B Pathways of Endothelial Cells in Diabetic Condition
por: Singh, Madhu V, et al.
Publicado: (2021)

Identification of the Factor That Leads Human Mesenchymal Stem Cell Lines into Decellularized Bone
por: Koyanagi, Anri, et al.
Publicado: (2022)

Involvement of Blnk and Foxo1 in tumor suppression in BCR-ABL1-transformed pro-B cells
por: Zhang, Ping, et al.
Publicado: (2021)

BCL11A promotes myeloid leukemogenesis by repressing PU.1 target genes
por: Sunami, Yoshitaka, et al.
Publicado: (2022)

Minichromosome Maintenance 2 Bound with Retroviral Gp70 Is Localized to Cytoplasm and Enhances DNA-Damage-Induced Apoptosis
por: Abe, Shinya, et al.
Publicado: (2012)

Targeting MCM2 function as a novel strategy for the treatment of highly malignant breast tumors
por: Abe, Shinya, et al.
Publicado: (2015)

Subcellular localization of MCM2 correlates with the prognosis of ovarian clear cell carcinoma
por: Aihemaiti, Gulinisha, et al.
Publicado: (2018)

B cell linker protein (BLNK) is a regulator of Met receptor signaling and trafficking in non-small cell lung cancer
por: Pathmanathan, Shivanthy, et al.
Publicado: (2022)

NOTCH1 pathway activating mutations and clonal evolution in pediatric T‐cell acute lymphoblastic leukemia
por: Kimura, Shunsuke, et al.
Publicado: (2019)

Curcumin alleviates experimental colitis via a potential mechanism involving memory B cells and Bcl-6-Syk-BLNK signaling
por: Wei, Si-Yi, et al.
Publicado: (2022)

Identification of BLNK and BTK as mediators of rituximab‐induced programmed cell death by CRISPR screens in GCB‐subtype diffuse large B‐cell lymphoma
por: Thomsen, Emil Aagaard, et al.
Publicado: (2020)

The RelB-BLNK Axis Determines Cellular Response to a Novel Redox-Active Agent Betamethasone during Radiation Therapy in Prostate Cancer
por: Chaiswing, Luksana, et al.
Publicado: (2022)

Relapsed acute lymphoblastic leukemia with unusual multiple bone invasions: A case report
por: HANGAI, MAYUMI, et al.
Publicado: (2014)

Quantitative high-throughput analysis of tumor infiltrating lymphocytes in breast cancer
por: Hayashi, Kumiko, et al.
Publicado: (2022)

JC Virus Inclusions in Progressive Multifocal Leukoencephalopathy: Scaffolding Promyelocytic Leukemia Nuclear Bodies Grow With Cell Cycle Transition Through an S-to-G2–Like State in Enlarging Oligodendrocyte Nuclei
por: Shishido-Hara, Yukiko, et al.
Publicado: (2014)

Integrated genetic and epigenetic analysis revealed heterogeneity of acute lymphoblastic leukemia in Down syndrome
por: Kubota, Yasuo, et al.
Publicado: (2019)

Circular RNA circBLNK promotes osteosarcoma progression and inhibits ferroptosis in osteosarcoma cells by sponging miR‑188‑3p and regulating GPX4 expression
por: Li, Zhongjun, et al.
Publicado: (2023)

COT-12 The role of clinical research professional in the registration study of pediatric solid tumor in Japan Children’s Cancer Group
por: Furukawa, Keiko, et al.
Publicado: (2020)

Correction for Bonilla et al., Adapter proteins SLP-76 and BLNK both are expressed by murine macrophages and are linked to signaling via Fcγ receptors I and II/III
Publicado: (2022)

ErbB2/Her2-dependent downregulation of a cell death-promoting protein BLNK in breast cancer cells is required for 3D breast tumor growth
por: Liu, Xiaoyang, et al.
Publicado: (2022)

EWS‐FLI1 regulates a transcriptional program in cooperation with Foxq1 in mouse Ewing sarcoma
por: Shimizu, Rikuka, et al.
Publicado: (2018)

Meis1 Is Required for the Maintenance of Postnatal Thymic Epithelial Cells
por: Hirayama, Takehiro, et al.
Publicado: (2014)

Cephalhematoma and petechial rashes associated with acute parvovirus B19 infection: a case report
por: Takeuchi, Masato, et al.
Publicado: (2013)

Precursor B Lymphoblastic Lymphoma Involving the Stomach
por: Iwamuro, Masaya, et al.
Publicado: (2013)

Spatial and Quantitative Analysis of Tumor-Associated Macrophages: Intratumoral CD163-/PD-L1+ TAMs as a Marker of Favorable Clinical Outcomes in Triple-Negative Breast Cancer
por: Shinohara, Hajime, et al.
Publicado: (2022)

The C/EBPβ LIP isoform rescues loss of C/EBPβ function in the mouse
por: Bégay, Valérie, et al.
Publicado: (2018)

Islet inflammation is associated with pancreatic fatty infiltration and hyperglycemia in type 2 diabetes
por: Horii, Tomomi, et al.
Publicado: (2020)

C/EBPα Expression is Partially Regulated by C/EBPβ in Response to DNA Damage and C/EBPα Deficient Fibroblasts Display an Impaired G(1) Checkpoint
por: Ranjan, Rakesh, et al.
Publicado: (2009)

Cannot write session to /tmp/vufind_sessions/sess_du6inv8fe7u0p052et6128kj2n