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Wnt7b Inhibits Osteoclastogenesis via AKT Activation and Glucose Metabolic Rewiring

The imbalance between bone formation and bone resorption causes osteoporosis, which leads to severe bone fractures. It is known that increases in osteoclast numbers and activities are the main reasons for increasing bone resorption. Although extensive studies have investigated the regulation of oste...

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Detalles Bibliográficos
Autores principales: Wu, Fanzi, Li, Boer, Hu, Xuchen, Yu, Fanyuan, Shi, Yu, Ye, Ling
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8645835/
https://www.ncbi.nlm.nih.gov/pubmed/34881243
http://dx.doi.org/10.3389/fcell.2021.771336