Immune Cell Plasticity Allows for Resetting of Phenotype From Effector to Regulator With Combined Inhibition of Notch/eIF5A Pathways

Type 1 diabetes (T1D) results from the destruction of pancreatic β-cells caused by an altered immune balance in the pancreatic microenvironment. In humans as well as in mouse models, T cells are well recognized as key orchestrators of T1D, which is characterized by T helper (Th) 1 and Th17 cell bias...

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Detalles Bibliográficos
Autores principales: Imam, Shahnawaz, Dar, Pervaiz, Aziz, Saba Wasim, Zahid, Zeeshan A., Sarwar, Haider, Karim, Tamanna, Faisal, Sarah, Haseeb, Ibrahim, Naqvi, Ahmed S., Shah, Rayyan, Haque, Amna, Salim, Nancy, Jaume, Juan C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Cell and Developmental Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8645838/
https://www.ncbi.nlm.nih.gov/pubmed/34881246
http://dx.doi.org/10.3389/fcell.2021.777805

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8645838/
https://www.ncbi.nlm.nih.gov/pubmed/34881246
http://dx.doi.org/10.3389/fcell.2021.777805

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