MiR-17-5p Inhibits TXNIP/NLRP3 Inflammasome Pathway and Suppresses Pancreatic β-Cell Pyroptosis in Diabetic Mice

Objective: Diabetes mellitus is a chronic progressive inflammatory metabolic disease with pancreatic β-cells dysfunction. The present study aimed to investigate whether miR-17-5p plays a protective effect on pancreatic β-cells function in diabetes mellitus (DM) mice and dissect the underlying mechan...

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Detalles Bibliográficos
Autores principales: Liu, Sijun, Tang, Ge, Duan, Fengqi, Zeng, Cheng, Gong, Jianfeng, Chen, Yanming, Tan, Hongmei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Cardiovascular Medicine
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8645844/
https://www.ncbi.nlm.nih.gov/pubmed/34881312
http://dx.doi.org/10.3389/fcvm.2021.768029

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8645844/
https://www.ncbi.nlm.nih.gov/pubmed/34881312
http://dx.doi.org/10.3389/fcvm.2021.768029

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