In vitro and in vivo modulation of NADPH oxidase activity and reactive oxygen species production in human neutrophils by α(1)-antitrypsin

Oxidative stress from innate immune cells is a driving mechanism that underlies COPD pathogenesis. Individuals with α-1 antitrypsin (AAT) deficiency (AATD) have a dramatically increased risk of developing COPD. To understand this further, the aim of this study was to investigate whether AATD present...

Descripción completa

Detalles Bibliográficos
Autores principales: Hawkins, Padraig, McEnery, Thomas, Gabillard-Lefort, Claudie, Bergin, David A., Alfawaz, Bader, Shutchaidat, Vipatsorn, Meleady, Paula, Henry, Michael, Coleman, Orla, Murphy, Mark, McElvaney, Noel G., Reeves, Emer P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: European Respiratory Society 2021
Materias:
Original Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8645872/
https://www.ncbi.nlm.nih.gov/pubmed/34881324
http://dx.doi.org/10.1183/23120541.00234-2021

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8645872/
https://www.ncbi.nlm.nih.gov/pubmed/34881324
http://dx.doi.org/10.1183/23120541.00234-2021

Ejemplares similares