Serpinc1 Acts as a Tumor Suppressor in Hepatocellular Carcinoma Through Inducing Apoptosis and Blocking Macrophage Polarization in an Ubiquitin-Proteasome Manner

Serpinc1 is a serine protease inhibitor in the coagulation cascade, but its role in tumor biology remains obscure. Here, we report an unexpected role of serpinc1 in suppression of hepatocellular carcinoma (HCC). In HCC patients, the mRNA and protein expression of serpinc1 is upregulated, which is ne...

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Detalles Bibliográficos
Autores principales: Xu, Dacai, Wu, Jiawen, Dong, Liang, Luo, Wenwen, Li, Lanying, Tang, Daolin, Liu, Jinbao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Oncology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8645897/
https://www.ncbi.nlm.nih.gov/pubmed/34881176
http://dx.doi.org/10.3389/fonc.2021.738607

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8645897/
https://www.ncbi.nlm.nih.gov/pubmed/34881176
http://dx.doi.org/10.3389/fonc.2021.738607

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