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Let-7a suppresses Ewing sarcoma CSCs’ malignant phenotype via forming a positive feedback circuit with STAT3 and lin28

Cancer stem cells (CSCs) have been documented to be closely related with tumor metastasis and recurrence, and the same important role were identified in Ewing Sarcoma (ES). In our previous study, we found that let-7a expression was repressed in ES. Herein, we further identified its putative effects...

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Detalles Bibliográficos
Autores principales: Xu, Jiang, Zhang, Zhongzu, Huang, Lu, Xiong, Jiachao, Zhou, Zhenhai, Yu, Honggui, Wu, Liang, Liu, Zhimin, Cao, Kai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8645918/
https://www.ncbi.nlm.nih.gov/pubmed/34917467
http://dx.doi.org/10.1016/j.jbo.2021.100406