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Let-7a suppresses Ewing sarcoma CSCs’ malignant phenotype via forming a positive feedback circuit with STAT3 and lin28
Cancer stem cells (CSCs) have been documented to be closely related with tumor metastasis and recurrence, and the same important role were identified in Ewing Sarcoma (ES). In our previous study, we found that let-7a expression was repressed in ES. Herein, we further identified its putative effects...
Autores principales: | Xu, Jiang, Zhang, Zhongzu, Huang, Lu, Xiong, Jiachao, Zhou, Zhenhai, Yu, Honggui, Wu, Liang, Liu, Zhimin, Cao, Kai |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8645918/ https://www.ncbi.nlm.nih.gov/pubmed/34917467 http://dx.doi.org/10.1016/j.jbo.2021.100406 |
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