Rapid-Onset Anti-Stress Effects of a Kappa-Opioid Receptor Antagonist, LY2795050, Against Immobility in an Open Space Swim Paradigm in Male and Female Mice

The kappa-opioid receptor (KOR) / dynorphin system is implicated with behavioral and neurobiological effects of stress exposure (including heavy exposure to drugs of abuse) in translational animal models. Thus some KOR-antagonists can decrease the aversive, depressant-like and anxiety-like effects c...

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Detalles Bibliográficos
Autores principales: Baynard, Caroline, Prisinzano, Thomas E., Butelman, Eduardo R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8645979/
https://www.ncbi.nlm.nih.gov/pubmed/34880762
http://dx.doi.org/10.3389/fphar.2021.775317

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8645979/
https://www.ncbi.nlm.nih.gov/pubmed/34880762
http://dx.doi.org/10.3389/fphar.2021.775317

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