Population Pharmacokinetics of Polymyxin B in Obese Patients for Resistant Gram-Negative Infections

Polymyxin B is an effective but potentially nephrotoxic antibiotic that is commonly used to treat resistant Gram-negative infections. As a weight-based dosing drug, obese patients may be at a high risk of nephrotoxicity. However, the pharmacokinetics and dosing recommendations for this population ar...

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Detalles Bibliográficos
Autores principales: Wang, Peile, Zhang, Qiwen, Feng, Min, Sun, Tongwen, Yang, Jing, Zhang, Xiaojian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8645997/
https://www.ncbi.nlm.nih.gov/pubmed/34880755
http://dx.doi.org/10.3389/fphar.2021.754844

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8645997/
https://www.ncbi.nlm.nih.gov/pubmed/34880755
http://dx.doi.org/10.3389/fphar.2021.754844

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