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Population Pharmacokinetics of Polymyxin B in Obese Patients for Resistant Gram-Negative Infections
Polymyxin B is an effective but potentially nephrotoxic antibiotic that is commonly used to treat resistant Gram-negative infections. As a weight-based dosing drug, obese patients may be at a high risk of nephrotoxicity. However, the pharmacokinetics and dosing recommendations for this population ar...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Frontiers Media S.A.
2021
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8645997/ https://www.ncbi.nlm.nih.gov/pubmed/34880755 http://dx.doi.org/10.3389/fphar.2021.754844 |