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Gene Expression Analysis of the Bone Marrow Microenvironment Reveals Distinct Immunotypes in Smoldering Multiple Myeloma Associated to Progression to Symptomatic Disease

BACKGROUND: We previously reported algorithms based on clinical parameters and plasma cell characteristics to identify patients with smoldering multiple myeloma (SMM) with higher risk of progressing who could benefit from early treatment. In this work, we analyzed differences in the immune bone marr...

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Detalles Bibliográficos
Autores principales: Isola, Ignacio, Brasó-Maristany, Fara, Moreno, David F., Mena, Mari-Pau, Oliver-Calders, Aina, Paré, Laia, Rodríguez-Lobato, Luis Gerardo, Martin-Antonio, Beatriz, Cibeira, María Teresa, Bladé, Joan, Rosiñol, Laura, Prat, Aleix, Lozano, Ester, Fernández de Larrea, Carlos
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8646031/
https://www.ncbi.nlm.nih.gov/pubmed/34880879
http://dx.doi.org/10.3389/fimmu.2021.792609