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Altered increase in STAT1 expression and phosphorylation in severe COVID‐19

The interferon pathway, a key antiviral defense mechanism, is being considered as a therapeutic target in COVID‐19. Both, substitution of interferon and JAK/STAT inhibition to limit cytokine storms have been proposed. However, little is known about possible abnormalities in STAT signaling in immune...

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Detalles Bibliográficos
Autores principales: Rincon‐Arevalo, Hector, Aue, Arman, Ritter, Jacob, Szelinski, Franziska, Khadzhynov, Dmytro, Zickler, Daniel, Stefanski, Luisa, Lino, Andreia C., Körper, Sixten, Eckardt, Kai‐Uwe, Schrezenmeier, Hubert, Dörner, Thomas, Schrezenmeier, Eva V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8646801/
https://www.ncbi.nlm.nih.gov/pubmed/34676541
http://dx.doi.org/10.1002/eji.202149575