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NMR‐Based Analysis of Nanobodies to SARS‐CoV‐2 Nsp9 Reveals a Possible Antiviral Strategy Against COVID‐19

Following the entry into the host cell, SARS‐CoV‐2 replication is mediated by the replication transcription complex (RTC) assembled through a number of nonstructural proteins (Nsps). A monomeric form of Nsp9 is particularly important for RTC assembly and function. In the present study, 136 unique na...

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Detalles Bibliográficos
Autores principales: Esposito, Gennaro, Hunashal, Yamanappa, Percipalle, Mathias, Venit, Tomas, Dieng, Mame Massar, Fogolari, Federico, Hassanzadeh, Gholamreza, Piano, Fabio, Gunsalus, Kristin C., Idaghdour, Youssef, Percipalle, Piergiorgio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8646926/
https://www.ncbi.nlm.nih.gov/pubmed/34705339
http://dx.doi.org/10.1002/adbi.202101113